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Generic pioglitazone is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Get Pioglitazone for as low as $9.76, which is 93% off the average retail price of $141.67 for the … Actos prices and discounts | AARP Prescription Discounts This drug may cause or make heart failure worse. Tell your doctor if you have had heart failure. Do not take this drug if you have moderate to severe heart failure or any signs of heart failure. You will be watched closely while starting this drug and if your dose is raised. Call your doctor right away if you have swelling in the arms or … Get the best price on Pioglitazone at pharmacies near you with SingleCare. Save up to 80% with our Pioglitazone coupons – with or without insurance! Compare Pioglitazone Hcl prices at 60,000+ US pharmacies. Get a free Rx.com coupon and save up to 90% on your prescription. 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