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How it works: Tretinoin belongs to the retinoid family and works by increasing skin cell turnover and stimulating collagen production. Transfer your prescription for RENOVA 0.02 % CREAM on Amazon Pharmacy. FREE SHIPPING for Prime members. Topical tretinoin is commonly used for acne. Compare Renova prices and find coupons that could save you up to 80% instantly at pharmacies near you such as CVS, Walgreens, Walmart, and many more. Renova is a topical retinoid that contains tretinoin 0.02% cream. Renova (tretinoin) can ease fine facial wrinkles, in addition to the regular use of sunscreen and sun-protective clothing. But it won't help get rid of deep wrinkles or hyperpigmentation from years of sun damage. Renova (tretinoin) is applied to the face once daily in the evening. This medication commonly causes skin irritation … What is RENOVA ® (tretinoin cream) 0.02%? RENOVA is a prescription medicine that may reduce fine facial wrinkles. 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