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Compare Xalatan (latanoprost) 0.005 % prices from verified online pharmacies or local U.S. pharmacies. Free coupons for xalatan (latanoprost). Discounts up to 80% off the retail price. XALATAN ® (latanoprost ophthalmic solution) is a prescription medication for the treatment of high eye pressure /intraocular pressure (IOP) in people with open-angle glaucoma or ocular hypertension. Latanoprost (Xalatan) is an eye drop medication. It's used in adults to treat conditions related to high pressure in the eye, such as glaucoma. It works as a prostaglandin to help with high eye pressure. The typical dosage is 1 drop in the affected eye (s) once each night. Side effects include feeling like there's something in the eye, burning, and stinging. Unopened bottles need to be … XALATAN ® (latanoprost ophthalmic solution) is a prescription medication for the treatment of high eye pressure /intraocular pressure (IOP) in people with open-angle glaucoma or ocular hypertension. 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