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This drug is also used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine. Hydrochlorothiazide – Overview Hydrochlorothiazide, sometimes marketed under brand names like Esidrix, Hydrodiuril, Microzide and Oretic, is a thiazide diuretic ("water pill") used to treat high blood pressure and fluid retention. People in need of a hydrochlorothiazide prescription can connect with a medical provider through Push Health who can prescribe the medication when appropriate. What … See RefillWise coverage for Microzide (Capsule) along with information on administration, interactions, dosage, side effects, and storage. Patient information and prices for Microzide Rx medication from leading online pharmacy. Learn more. Sanford Pharmacy can assist in answering these and other medicine-related queries. The Microzide 12.5 mg dose is commonly prescribed as an initial treatment for mild hypertension. How to Use Microzide? Microzide usage information appears in the following notes which show how physicians handle the drug during their standard medical practice. Microzide is a hydrochlorothiazide-based thiazide diuretic used for long-term blood pressure control and mild fluid management. Microzide 12.5 mg, hydrochlorothiazide 25 mg used for hypertension, microzide side effects, and common combinations like lisinopril hydrochlorothiazide or losartan hydrochlorothiazide all sit within that same approach. Microzide 25mg is a prescription medication mainly used to treat high blood pressure and swelling caused by fluid retention. Its active ingredient is hydrochlorothiazide 25 mg, a water pill (diuretic) that helps your body get rid of extra salt and water through urine. You can take it with or without food. If it upsets your stomach, take it with food. 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